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| Incomplet Please contact
us when you have a publication resulting from a Mail-in project. |
| Collected
at |
2008 |
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Insights into the structural variation between pentapeptide repeat proteins-Crystal structure of Rfr23 from Cyanothece 51142. Medline Abstract PDB file 2O6W |
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Functional and Structural Characterization of DR_0079 from Deinococcus radiodurans, a Novel Nudix Hydrolase with a Preference for Cytosine (Deoxy)ribonucleoside 5'-Di- and Triphosphates. Medline Abstract PDB file |
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Chen
G, Wang H, Robinson H, Cai
J, Wan Yand Ke H. An insight into the pharmacophores of phosphodiesterase-5 inhibitors from synthetic and crystal structural studies. Biochem Pharmacol. 75 1717-28 (2008). Medline Abstract PDB files 2QYN , 2QYM , 2QYL and 2QYK |
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Crystal structure of the lysine riboswitch regulatory mRNA element. J Biol Chem. 2008 Jul 1. [Epub ahead of print] Medline Abstract PDB files 3D0U and 3D0X |
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| Greenhagen
BT, Shi K, Robinson H,
Gamage S, Bera AK, Ladner JE and Parsons JF. Crystal Structure of the Pyocyanin Biosynthetic Protein PhzS. Biochemistry. 47 5281-9 (2008). Medline Abstract PDB file 2RGJ |
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Crystal Structure and RNA Binding of the Tex Protein from Pseudomonas aeruginosa. J. Mol. Biol. 377 1460-73 (2008). Medline Abstract PDB files 3BZC and 3BZK |
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Hall
BM, Roberts SA, Heroux A
and
Cordes M. Two structures of a λ Cro variant highlight dimer flexibility but disfavor major dimer distortions upon binding of cognate DNA. J. Mol.Biol. 375 802-11 (2008). Medline Abstract PDB files 2OVG and 2ECS |
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Crystal structure of human kynurenine aminotransferase II. Medline Abstract PDB files 2R2N and 2QLR |
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Structural insight into the mechanism of substrate
specificity of aedes kynurenine aminotransferase. Biochemistry 47 1622-30 (2008) epub Medline Abstract PDB file 2R2N |
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Pallana
PS, Ittig D, Héroux A,
Wawrzak Z, Leumann CJ and Egli M. Crystal structure of tricyclo-DNA: an unusual compensatory change of two adjacent backbone torsion angles. Chem. Commun. (Camb). 7 883-5 (2008). .Medline Abstract;PDB file 2RF3 |
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Petrie
EJ, Clements CS, Lin J, Sullivan LC, Johnson D, Huyton T, Heroux A, Hoare HL, Beddoe T,
Reid HH, Wilce MC, Brooks AG, and Rossjohn J. CD94-NKG2A recognition of human leukocyte antigen (HLA)-E bound to an HLA class I leader sequence. J. Exp. Med. 205 725-35 (2008). Medline Abstract;PDB file 3CDG |
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| Podzelinska
K., He S., Soares A., Zechel D. , Hove-Jensen B.
and Jia Z. Expression, purification and preliminary diffraction studies of PhnP. Acta Cryst. F64, 554-557 (2008). [ doi:10.1107/S1744309108014656 ] |
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Structural basis for accelerated cleavage of bovine pancreatic trypsin inhibitor (BPTI) by human mesotrypsin. Medline Abstract; PDB files 2RA3 and 2R9P |
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Vandemark
AP, Xin H, McCullough L, Rawlins R, Bentley S, Heroux A, Stillman DJ, Hill CP
andFormosa T. Structural and functional analysis of the Spt16p N-terminal domain reveals overlapping roles of yFACT subunits. J Biol Chem. epub dec 18, 2007 Medline Abstract ; PDB files 3BIT , 3BIQ and 3BIP |
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Crystal Structure of a
Complex between the Phosphorelay Protein YPD1
and the Response Regulator Domain of SLN1 Bound to a Phosphoryl Analog. J. M. Biol 375 1141-51(2008). Medline Abstract; PDB file 2R25, |
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| 2007 |
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| X12C X29 |
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Carra
JH, McHugh CA, Mulligan S, Machiesky LM, Soares AS and Millard CB. Fragment-based identification of determinants of conformational and spectroscopic change at the ricin active site. BMC Struct. Biol. 7 72 (2007). Medline Abstract PDB files 2PJO, 2PJN, 2R2X, 2R3D and 2P8N |
| X29 |
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Fisher
RD, Chung HY, Zhai Q, Robinson H,Sundquist
WI and Hill CP. Structural and Biochemical Studies of ALIX/AIP1 and Its Role inRetrovirus Budding. Cell 128 841-52 (2007). Medline Abstract PDB files 2OEX, 2OEV and 2EOW |
| X29 |
Keiski
CL, Yip P, Robinson H,
Burrows LL, Howell PL. Expression, purification, crystallization and preliminary X-ray analysis of Pseudomonas fluorescens AlgK. Acta Cryst. F63 415-8 (2007) . Medline Abstract PDB file |
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Kelly
BN, Kyere S, Kinde I, Tang C, Howard BR, Robinson H, Sundquist WI,
Summers MF, Hill CP. Structure of the Antiviral Assembly Inhibitor CAP-1 Complex with the HIV-1 CA Protein. J. Mol Biol. 373, 355-366 (2007). Medline Abstract PDB files 2PRX , 2JPR , 2PWO and 2PWM |
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| X29 |
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Kim
SK, Robinson H,
Nelson BC, Ready PT and Ladner JE Crystal Structure of Yersinia pestis Chorismate Mutase To be Published Medline Abstract PDB file 2GBB |
| X29,X12B |
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Kvansakul
M, van Delft M,
Lee E, Gulbis J, Fairlie W,
D Huang and P
Colman. A Structural Viral Mimic of Prosurvival Bcl-2: A Pivotal Role for Sequestering Proapoptotic Bax and Bak. Mol. Cell 25 933-942 (2007). Medline Abstract PDB files 2JBX and 2JBY |
| X12B |
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Hewitson KS, Liénard
BM,
McDonough MA, Clifton I, Butler D, Soares
AS, Oldham NJ, McNeill LA, Schofield CJ. Structural and Mechanistic Studies on the Inhibition of the Hypoxia-Inducible Transcription Factor Hydroxylases by Tricarboxylic Acid Cycle Intermediates. J Biol Chem. 282 3293 (2007). Medline Abstract; PDB files 2CGO and 2CGN |
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Mans J,
Natarajan K, Balbo A, Schuck P, Eikel D, Hess S, Robinson H, Simic H, Jonjic S,
Tiemessen CT, Margulies DH.
J Biol Chem.
282 35247-58 (2007).Cellular expression and crystal structure of the murine cytomegalovirus MHC-Iv glycoprotein, m153. Medline Abstract; PDB file 2O5N |
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| X29 |
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Moore
BA, Robinson HH and
Xu Z. The Crystal Structure of Mouse Exo70 Reveals Unique Features of the Mammalian Exocyst. J Mol Biol. 371 1141-50 (2007). Medline Abstract; PDB file 2PFV |
| X29 |
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Oruganti
S, Zhang Y, Li H, Robinson H,
Terns MP, Terns RM, Yang W, Li H. Alternative Conformations of the Archaeal Nop56/58-Fibrillarin Complex Imply Flexibility in Box C/D RNPs. J Mol Biol. 371 1141-50 (2007). Medline Abstract; PDB file 2NNW |
| X29 |
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Parson
JF, Greenhagen BT, Shi K, Calabrese K, Robinson H, Ladner JE. Structural and functional analysis of the pyocyanin biosynthetic protein PhzM from Pseudomonas aeruginosa. Biochemistry 46 1821-8 (2007). Medline Abstract; PDB file 2IP2 |
| X29 |
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Pfister
TD, Mirareli AY, Gengenbach AJ, Zhaoi X, Danstrom C, Conaster N, Gao
YG, Robinson H, Zukoski
CF, Wang AH and LuY. Kinetic and crystallographic studies of a redesigned manganese-binding site in cytochrome c peroxidase. J Biol Inorg Chem. 1 126-37 (2007). Medline Abstract; PDB file 2IA8 and 2ICV |
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Vandemark
AP, Kasten MM, Ferris E, Heroux A,
Hill CP, Cairns BR. Autoregulation of the rsc4 tandem bromodomain by gcn5 acetylation. Mol Cell. 27 817-28 (2007). Medline Abstract; PDB file 2R0S , 2R0V, 2R0Y and 2R10 |
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| X4A,
X26C RapiData |
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Widboom
PF, Fielding EN, Liu Y, Bruner SD. Structural basis for co-factor-independant dioxygenase in vancomycin biosynthesis. Nature 447 342-345 (2007). Medline Abstract; PDB files 2NP9 and 2PG8 |
| X29 |
Wang
H, Peng M, Chen Y, Geng J, Robinson
H, Houslay MD, Cai J, Ke H. Structures of the four subfamilies of phosphodiesterase-4 provide insight into the selectivity of their inhibitors. Biochem J. 408 193-201 (2007). Medline Abstract; PDB files 2QYK , 2QYL, 2QYM and 2QYN |
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| X29 |
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Wang
H, Liu Y, Hou J, Zheng M, Robinson
H and Ke H. Structural insight into substrate specificity of phosphodiesterase 10. Proc Natl Acad Sci U S A (2007). Medline Abstract; PDB files 2OUN, 2OUP, 2OUQ, 2OUR 2OUS, 2OUU, 2OUV and 2OUY |
| X29 |
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Wang
H, Robinson
H and Ke H. The Molecular Basis for Different Recognition of Substrates by Phosphodiesterase Families 4 and 10. J. Mol. Biol. 371, 302-307 (2007).  Medline Abstract; PDB file 2PW3 |
| X29 |
Wang H, Ye M,
Robinson H, Francis
SH, Ke H.
Mol Pharmacol. (2007).Conformational variations of both PDE5 and inhibitors provide the structural basis for the physiological effects of vardenafil and sildenafil. Medline Abstract; PDB file 3B2R |
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Welch
BD, Vandemark AP, Heroux A, Hill CP, Kay MS. Potent D-peptide inhibitors of HIV-1 entry. Proc Natl Acad Sci U S A. 104 16828-33 (2007). Medline Abstract; PDB files 2R3C , 2R5B and 2R5D |
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| X29 |
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Zhang
L, Shen J, Guarnieri MT, Heroux A, Yang K and Zhao R. Crystal structure of the C-terminal domain of splicing factor Prp8 carrying retinitis pigmentosa mutants. Protein Sci. 2007 May 1; [Epub ahead of print] Medline Abstract; PDB files 2P87 and 2P8R |
| X29 |
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ZhangY,
Cao R, Leon A, Guo RT, Krysiak K, Yin F,
Hudock MP, Mukherjee S, Gao YG, Robinson H, Song Y, No JH, Hong
W, Morita C, Wang AH-J, Oldfield E.
Bisphosphonates: Teaching Old Drugs with New Tricks To be Published PDB files 2OPN 2OPM and 2OGD |
| 2006 |
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| X29 |
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Alam
SL, Langelier C, Whitby FG, Koirala S, Robinson H, Hill CP, Sundquist
WI. Structural basis for ubiquitin recognition by the human ESCRT-II EAP45 GLUE domain. Nat Struct Mol Biol. 11 1029-30 (2006). Medline Abstract; PDB file 2HTH |
| X29 |
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Buchko
GW, Ni S, Robinson H,
Welsh EA, Pakrasi HB, Kennedy MA. Characterization of two potentially universal turn motifs that shape the repeated five-residues fold--crystal structure of a lumenal pentapeptide repeat protein from Cyanothece 51142. Protein Sci. 11 2579-95 (2006). Medline Abstract; PDB files 2F3L and 2G0Y |
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Buchko
GW, Ni S, Robinson H,
Welsh EA, Pakrasi HB, Kennedy MA. Cloning, expression, crystallization and preliminary crystallographic analysis of a pentapeptide-repeat protein (Rfr23) from the bacterium Cyanothece 51142. Acta Cryst. F62 1251-4 (2006). Medline Abstract; PDB files 2F3L and 2G0Y |
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| X12B |
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Copeland DM, Soares
AS, West AH, Richter-Addo GB. Crystal structures of the nitrite and nitric oxide complexes of horse heart myoglobin. J Inorg Biochem.; 100 1413-25 (2006). Medline Abstract; PDB file 2FRF |
| X26C |
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Gallager
DT, Smith NN, KIM SK, Heroux A, Robinson
H and Reddy PT. Structure of the Class IV Adenylyl Cyclase Reveals a Novel Fold. J Mol Biol. (2006). Medline Abstract; related PDB file 2FJT |
| X26C |
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Ghosh
AK, Sridhar PR, Leshchenko S, Hussain AK, Li J, Kovalevsky AY, Walters
DE, Wedekind JE, Grum-Tokars V, Das D, Koh Y, Maeda K, Gatanaga H,
Weber IT and Mitsuya H. Structure-based design of novel HIV-1 protease inhibitors to combat drug resistance. J Med Chem. 49 5252-61 (2006). Medline Abstract; PDB file 2HB3 |
| X25 |
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Han
Q, Robinson H, Gao YG,
Vogelaar N, Wilson SR, Rizzi M and Li J. Crystal structures of Aedes aegypti alanine glyoxylate aminotransferase. J Biol Chem. (2006) Medline Abstract; PDB files 2HUF, 2HUI and 2HUU |
| X26C,
X25 |
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Huai Q, Sun Y, Wang H,
Macdonald D, Aspiotis R, Robinson
H, Huang Z and Ke H. Enantiomer Discrimination Illustrated by the High Resolution Crystal Structures of Type 4 Phosphodiesterase. J Med Chem. 49 1867-1873 (2006). Medline Abstract; PDB files 2FM0 and 2FM5 |
| X29 |
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Kelly
NB, Howard BR, Wang H, Robinson H,
Sundquist WI and Hill CP. Implications for Viral Capsid Assembly from Crystal Structures of HIV-1 Gag(1)(-)(278) and CA(N)(133)(-)(278)(,). Biochemistry. 45 11257-66 (2006). Medline Abstract; PDB files 2GOL and 2GON |
| X29 |
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Mao J, Mukherjee S, Zhang, Y, Cao R, Sanders JM, Song Y, Zhang Y, Meints GA, Gao YG, Mukkamala, D, Hudock, MP, Oldfield E. Solid-state NMR, crystallographic, and computational investigation of bisphosphonates and farnesyl diphosphate synthase-bisphosphonate complexes. J.Am.Chem.Soc. 128 14485-14497
(2006). Medline Abstract; PDB file 2I19 |
| X12B |
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McDonough
MA, Li V, Flashman E, Chowdhury R, Mohr C, Lienard BM, Zondlo J, Oldham
NJ, Clifton IJ, Lewis J, McNeill LA, Kurzeja RJ, Hewitson KS, Yang E,
Jordan S, Syed RS, Schofield CJ. Cellular oxygen sensing: Crystal structure of hypoxia-inducible factor prolyl hydroxylase (PHD2). Proc Natl Acad Sci U S A. 103 9814-9 (2006). Medline Abstract; related PDB files 2GIM and 2G19 |
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Meinke G, Bullock PA and
Bohm A. Crystal Structure of the simian virus 40 large T-antigen origin-binding domain. J Virol. 80 4304-4312 (2006). Medline Abstract; PDB file 2FUF |
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| X26C |
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Natarajan
K, Hicks A, Mans J, Robinson H,
Guan R, Mariuzza RA and Margulies
DH. Crystal structure of the murine cytomegalovirus MHC-I homolog m144. J Mol Biol. 358(1) 157-71 (2006). Medline Abstract; PDB files 1U58 and 1PQZ |
| X12C |
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Ni S, Forouhar F, Bussiere DE, Robinson H
and
Kennedy MA. Crystal structure of VC0702 at 2.0 A: conserved hypothetical protein from Vibrio cholerae. Proteins. 63 733-41 (2006) Medline Abstract; PDB file 1ZNO |
| X26C |
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Pena
PV, Davrazou F, Shi X, Walter K, Verkhusha
VV, Gozani O, Zhao R and Kutateladze TG. Molecular mechanism of H3K4Me3 recognition by Plant Homeodomain of Inhibitor of Growth 2 tumor suppressor. Nature 442 100-103 (2206). Medline Abstract; PDB file native 2g6q |
| X26C |
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Reyes-Turcu
FE, Horton JR, Mullally JE, Heroux
A, Cheng X and Wilkinson KD. The Ubiquitin Binding Domain ZnF UBP Recognizes the C-Terminal Diglycine Motif of Unanchored Ubiquitin Cell 124 1197-1195 (2006). Medline Abstract; PDB files 2G43 and 2G45 |
| X25,X29 |
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Sanghani PC, Davis WI,
Zhai L and Robinson H. Structure-function relationships in human glutathione-dependent formaldehyde dehydrogenase. Role of Glu-67 and Arg-368 in the catalytic mechanism. Biochemistry 18 4819-30 (2006). Medline Abstract; PDB files 2FZE and 2FZW |
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Schubert
HL, Hill CP. Structure of ATP-Bound Human ATP:Cobalamin Adenosyltransferase. Biochemistry 45 15188-96 (2006). Medline Abstract; PDB file 2IDX |
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| X26C |
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Vandemark
AP, Blanksma M, Ferris E, Heroux A,
Hill CP, Formosa T The Structure of the yFACT Pob3-M Domain, Its Interaction with the DNA Replication Factor RPA, and a Potential Role in Nucleosome Deposition. Mol Cell. 22 363-74 (2006). Medline Abstract; PDB files 2GCL and 2GCJ |
| X29 |
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Wang
H, Liu Y, Huai Q, Cai J, Zoraghi R, Francis SH, Corbin JD, Robinson H,
Xin Z, Lin G, Ke H. Multiple conformations of phosphodiesterase-5: implications for enzyme function and drug development. J Biol Chem. May 30 (2006) Medline Abstract; PDB files 2H44, 2H40 and 2H42 |
| 2005 |
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| X26C |
 |
Auperin
TC,
Bolduc GR, Baron MJ, Heroux A, Filman DJ, Madoff LC and Hogle JM. Crystal Structure of the N-terminal domain of group B Streptococcus Alpha C Protein J Biol Chem. 280 8245-52 (2005) Medline Abstract; PDB file 1YWM |
| X29 |
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Bitto
E, Bingman CA, Robinson H, Allard STM, Wesenberg GE and Phillips Jr. GN
The structure at 2.5 Å resolution of human basophilic leukemia-expressed protein BLES03 Acta Cryst. F61 812-817 (2005) Medline Abstract; PDB file 1ZTP |
| X29 |
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Brown
JH, Zhou Z, Reshetnikova L, Robinson H, Yammani RD, Tobacman LS and
Cohen
C. Structure of the mid-region of tropomyosin: Bending and binding sites for actin. Proc Natl Acad Sci U S A. 102 18878-83 (2005) Medline Abstract; PDB file 2B9C |
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Chen F, Sun H, Zhang Y, Mukkamala D and Oldfield E. A solid state 13C NMR, crystallographic, and quantum chemical investigation of chemical shifts and hydrogen bonding in histidine dipeptides. J.Am.Chem.Soc. 127 12544-12554
(2005).Medline Abstract; PDB file 2EWG |
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| X25 |
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Forster A, Masters EI, Whitby
FG, Robinson H and Hill CP. The 1.9 A Structure of a Proteasome-11S Activator Complex and Implications for Proteasome-PAN/PA700 Interactions. Mol Cell. 27 589-99 (2005) Medline Abstract; PDB files 1YA7, 1YAU , 1Z7Q and 1YAR |
| X12C |  |
Han
Q, Gao YG, Robinson H,
Ding H, Wilson S and Li J. Crystal structures of Aedes aegypti kynurenine |